MolNFT v1 · #206763 · protein
AlphaFold monomer V2.0 prediction for leucine-rich repeat-containing protein 37A2 (A6NM11)
A6NM11: “AlphaFold monomer V2.0 prediction for leucine-rich repeat-containing protein 37A2 (A6NM11)”. 10 pockets (best druggability 0.70). MolNFT v1 #206763 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A6NM11
- Type
- protein
- Length
- 1,700 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x91C297d31a64ea1ebCc9f529C46831f1138abe26
- Molecule
- Leucine-rich repeat-containing protein 37A2
- UniProt
- A6NM11
- Pockets
- 10 · best druggability 0.70
Structure
1 distinct chain · 13% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Leucine-rich repeat-containing protein 37A2 | protein | 1700 | 13% helix, 3% strand | A6NM11 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 567 | 0.70 | 0.79 | 45 | empty |
| 2 | 498 | 0.63 | 0.75 | 45 | empty |
| 3 | 532 | 0.62 | 0.75 | 42 | empty |
| 4 | 218 | 0.51 | 0.76 | 31 | empty |
| 5 | 196 | 0.47 | 0.75 | 31 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A6NM11
- Elsewhere: UniProt A6NM11 · AlphaFold DB A6NM11
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