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AlphaFold monomer V2.0 prediction for leucine-rich repeat-containing protein 37A2 (A6NM11)

Analyse AlphaFold monomer V2.0 prediction for leucine-rich repeat-containing protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A6NM11
Type
protein
Length
1,700 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x91C297d31a64ea1ebCc9f529C46831f1138abe26
Molecule
Leucine-rich repeat-containing protein 37A2
UniProt
A6NM11
Pockets
10 · best druggability 0.70

Structure

1 distinct chain · 13% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALeucine-rich repeat-containing protein 37A2protein170013% helix, 3% strandA6NM11

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15670.700.7945empty
24980.630.7545empty
35320.620.7542empty
42180.510.7631empty
51960.470.7531empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

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