MolNFT v1 · #155728 · protein
AlphaFold monomer V2.0 prediction for glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (P21695)
P21695: “AlphaFold monomer V2.0 prediction for glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (P21695)”. 4 pockets (best druggability 0.76). MolNFT v1 #155728 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P21695
- Type
- protein
- Length
- 349 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3639908Ea9460962ad4f6d308d2b32E104BaF088
- Molecule
- Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
- UniProt
- P21695
- Pockets
- 4 · best druggability 0.76
Structure
1 distinct chain · 55% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic | protein | 349 | 55% helix, 16% strand | P21695 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 393 | 0.76 | 0.85 | 41 | empty |
| 2 | 50 | 0.33 | 0.78 | 16 | empty |
| 3 | 57 | 0.31 | 0.76 | 17 | empty |
| 4 | 51 | 0.27 | 0.74 | 15 | empty |
Compared structures
- 1X0X · Co-Structure of Homo Sapiens Glycerol-3-Phosphate Dehydrogenase 1 complex with NAD · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1X0X · Co-structure of homo sapiens glycerol-3-phosphate dehydrogenase 1 complex with NAD · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1X0V · Crystal structure of homo sapien glycerol-3-phosphate dehydrogenase 1 · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 1X0V · Crystal Structure of Homo Sapien Glycerol-3-Phosphate Dehydrogenase 1 · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 1WPQ · Ternary Complex Of Glycerol 3-phosphate Dehydrogenase 1 with NAD and dihydroxyactone · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 1WPQ · Ternary complex of glycerol 3-phosphate dehydrogenase 1 with NAD and dihydroxyactone · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6E90 · Ternary complex of human glycerol 3-phosphate dehydrogenase · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6E90 · Ternary complex of human glycerol 3-phosphate dehydrogenase · an experimental structure of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21695
- Elsewhere: UniProt P21695 · AlphaFold DB P21695
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