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Hedycaryol apo

Analyse Hedycaryol apo in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4MC0
Type: protein
Length: 581 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative sesquiterpene cyclase
EC: 4.2.3.-
UniProt: E4MYY0
Pockets: 3 · best druggability 0.75

Structure

x-ray diffraction · 2 distinct chains · 75% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative sesquiterpene cyclase (EC 4.2.3.-)	protein	291	75% helix, 0% strand	E4MYY0
B	Putative sesquiterpene cyclase (EC 4.2.3.-)	protein	290	74% helix, 0% strand	E4MYY0

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	644	0.75	0.81	44	empty
2	627	0.74	0.81	44	empty
3	75	0.34	0.76	16	empty

Interfaces

1 interface between chains.

A–B · 666 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

4MC0 · Hedycaryol apo · the same entry in another collection · chain A against A, TM-score 1.00
E4MYY0 · AlphaFold monomer V2.0 prediction for (2Z,6E)-hedycaryol synthase (E4MYY0) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E4MYY0
Elsewhere: RCSB PDB 4MC0 · PDBe 4MC0 · UniProt E4MYY0

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