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Crystal structure of oxidized HN33/TUSC3

Analyse Crystal structure of oxidized HN33/TUSC3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4M90
Type: protein
Length: 154 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tumor suppressor candidate 3
UniProt: Q13454
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tumor suppressor candidate 3	protein	154	47% helix, 15% strand	Q13454

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.53	0.87	20	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4M90 · crystal structure of oxidized hN33/Tusc3 · the same entry in another collection · chain A against A, TM-score 1.00
Q13454 · AlphaFold monomer V2.0 prediction for tumor suppressor candidate 3 (Q13454) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13454
Elsewhere: RCSB PDB 4M90 · PDBe 4M90 · UniProt Q13454

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