Research workbench
Fungal protein
Analyse Fungal protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4M8B
- Type
- protein + DNA
- Length
- 221 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chain a of dsdna containing the cis-regulatory element; Chain B of dsdna containing the…
- UniProt
- P38867
- Pockets
- 3 · best druggability 0.58
Structure
x-ray diffraction · 3 distinct chains · 26% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chain a of dsdna containing the cis-regulatory element | dna | 20 | — | — |
| B | Chain B of dsdna containing the cis-regulatory element | dna | 20 | — | — |
| R | YHR177W | protein | 181 | 26% helix, 28% strand | P38867 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · chains A, R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 286 | 0.58 | 0.78 | 35 | empty |
| 2 | 167 | 0.47 | 0.76 | 22 | empty |
| 3 | 182 | 0.45 | 0.75 | 26 | empty |
Interfaces
3 interfaces between chains.
- A–B · 862 Ų buried · 97 hydrogen bonds · nucleic-nucleic
- B–R · 620 Ų buried · 19 hydrogen bonds · protein-nucleic
- A–R · 594 Ų buried · 10 hydrogen bonds · protein-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38867
- Elsewhere: RCSB PDB 4M8B · PDBe 4M8B · UniProt P38867
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