Research workbench
OYE2.6 Y78W, I113C
Analyse OYE2.6 Y78W, I113C in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4M5P
- Type
- protein
- Length
- 404 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NADPH dehydrogenase
- UniProt
- A3LT82
- Ligands
- FMN, 23W, NA
- Pockets
- 1 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADPH dehydrogenase | protein | 404 | 41% helix, 15% strand | A3LT82 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · chains A
- 23W · methyl 2-(hydroxymethyl)prop-2-enoate · ligand · chains A
- NA · Sodium ion · metal · 3 copies · chains A
- MLA · Malonic acid · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 269 | 0.77 | 0.90 | 41 | FMN, MLA, 23W |
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 4M5P · OYE2.6 Y78W, I113C · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A3LT82
- Elsewhere: RCSB PDB 4M5P · PDBe 4M5P · UniProt A3LT82
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.