Research workbench
Crystal structure of non-heme iron oxygenase orfp
Analyse Crystal structure of non-heme iron oxygenase orfp in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4M23
- Type
- protein
- Length
- 1,281 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-arginine beta-hydroxylase
- UniProt
- G9MBV2
- Pockets
- 14 · best druggability 0.81
Structure
x-ray diffraction · 4 distinct chains · 35% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-arginine beta-hydroxylase | protein | 332 | 36% helix, 20% strand | G9MBV2 |
| B | L-arginine beta-hydroxylase | protein | 314 | 36% helix, 21% strand | G9MBV2 |
| C | L-arginine beta-hydroxylase | protein | 319 | 34% helix, 21% strand | G9MBV2 |
| D | L-arginine beta-hydroxylase | protein | 316 | 35% helix, 21% strand | G9MBV2 |
Pockets
14 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 405 | 0.81 | 0.89 | 72 | empty |
| 2 | 523 | 0.80 | 0.86 | 81 | empty |
| 3 | 437 | 0.78 | 0.86 | 41 | empty |
| 4 | 885 | 0.75 | 0.79 | 106 | empty |
| 5 | 1151 | 0.74 | 0.77 | 90 | empty |
Interfaces
4 interfaces between chains.
- C–D · 1607 Ų buried · 39 hydrogen bonds · protein-protein
- A–B · 1563 Ų buried · 32 hydrogen bonds · protein-protein
- B–C · 395 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 14 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4M23 · Crystal structure of non-heme iron oxygenase OrfP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G9MBV2
- Elsewhere: RCSB PDB 4M23 · PDBe 4M23 · UniProt G9MBV2
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