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The crystal structure of a functionally unknown protein LPG2422 from legionella pneumophila subsp. pneumophila str. philadelphia 1
Analyse The crystal structure of a functionally unknown protein LPG2422 from legionella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4M0M
- Type
- protein
- Length
- 721 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative uncharacterized protein
- UniProt
- Q5ZSU4
- Ligands
- PO4
- Pockets
- 5 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative uncharacterized protein | protein | 721 | 52% helix, 9% strand | Q5ZSU4 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A
- PG4 · Tetraethylene glycol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 840 | 0.82 | 0.84 | 72 | PG4 |
| 2 | 231 | 0.64 | 0.82 | 29 | PG4 |
| 3 | 319 | 0.61 | 0.78 | 37 | empty |
| 4 | 195 | 0.55 | 0.79 | 24 | empty |
| 5 | 65 | 0.29 | 0.74 | 17 | empty |
Modifications
Observed in the structure: 13 modified (engineered).
Compared structures
- 4M0M · The crystal structure of a functionally unknown protein lpg2422 from Legionella… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZSU4
- Elsewhere: RCSB PDB 4M0M · PDBe 4M0M · UniProt Q5ZSU4
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