Research workbench
Crystal structure of inclusion body protein (pixa PFAM12306) from burkholderia cenocepacia J2315
Analyse Crystal structure of inclusion body protein (pixa PFAM12306) from burkholderia… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4LZK
- Type
- protein
- Length
- 975 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pixa inclusion body protein
- UniProt
- B4EII9
- Pockets
- 19 · best druggability 0.71
Structure
x-ray diffraction · 6 distinct chains · 6% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pixa inclusion body protein | protein | 159 | 6% helix, 54% strand | B4EII9 |
| B | Pixa inclusion body protein | protein | 166 | 6% helix, 53% strand | B4EII9 |
| C | Pixa inclusion body protein | protein | 174 | 7% helix, 51% strand | B4EII9 |
| D | Pixa inclusion body protein | protein | 158 | 6% helix, 52% strand | B4EII9 |
| E | Pixa inclusion body protein | protein | 157 | 6% helix, 52% strand | B4EII9 |
| F | Pixa inclusion body protein | protein | 161 | 6% helix, 53% strand | B4EII9 |
Pockets
19 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 148 | 0.71 | 0.90 | 28 | empty |
| 2 | 237 | 0.70 | 0.87 | 48 | empty |
| 3 | 263 | 0.70 | 0.86 | 31 | empty |
| 4 | 218 | 0.69 | 0.87 | 46 | empty |
| 5 | 201 | 0.69 | 0.87 | 30 | empty |
Interfaces
13 interfaces between chains.
- A–C · 1903 Ų buried · 15 hydrogen bonds · protein-protein
- D–E · 1260 Ų buried · 9 hydrogen bonds · protein-protein
- B–F · 1250 Ų buried · 4 hydrogen bonds · protein-protein
- A–B · 944 Ų buried · 17 hydrogen bonds · protein-protein
- E–F · 844 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 13 modified (engineered).
Compared structures
- 4LZK · Crystal structure of inclusion body protein (PixA pfam12306) from Burkholderia… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4EII9
- Elsewhere: RCSB PDB 4LZK · PDBe 4LZK · UniProt B4EII9
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