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Human CARMA1 card domain

Analyse Human CARMA1 card domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4LWD
Type: protein
Length: 90 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Caspase recruitment domain-containing protein 11
UniProt: Q9BXL7
Ligands: MG, SO4
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 66% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Caspase recruitment domain-containing protein 11	protein	90	66% helix, 0% strand	Q9BXL7

Ligands and binding sites

MG · Magnesium ion · metal · chains A
SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.36	0.76	14	empty

Compared structures

4LWD · Human CARMA1 CARD domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9BXL7 · AlphaFold monomer V2.0 prediction for caspase recruitment domain- containing protein 11… · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BXL7
Elsewhere: RCSB PDB 4LWD · PDBe 4LWD · UniProt Q9BXL7

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