Research workbench
Crystallization and structural analysis of 2-hydroxyacid dehydrogenase from ketogulonicigenium vulgare Y25
Analyse Crystallization and structural analysis of 2-hydroxyacid dehydrogenase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4LSW
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- D-2-hydroxyacid dehydrogensase protein
- UniProt
- E3F052
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | D-2-hydroxyacid dehydrogensase protein | protein | 318 | 41% helix, 18% strand | E3F052 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 523 | 0.67 | 0.78 | 48 | empty |
| 2 | 129 | 0.42 | 0.76 | 24 | empty |
Compared structures
- 4LSW · Crystallization and Structural Analysis of 2-Hydroxyacid Dehydrogenase from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E3F052
- Elsewhere: RCSB PDB 4LSW · PDBe 4LSW · UniProt E3F052
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