Research workbench

Crystal structure of monomeric ligand binding domain of S. typhimurium cysb, a lysr transcriptional regulator at 2.2A

Analyse Crystal structure of monomeric ligand binding domain of S. typhimurium cysb, a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4LP2
Type: protein
Length: 239 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hth-type transcriptional regulator cysb
UniProt: P06614
Pockets: 1 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Hth-type transcriptional regulator cysb	protein	239	33% helix, 25% strand	P06614

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.38	0.81	15	empty

Compared structures

4LP2 · Crystal structure of monomeric ligand binding domain of S. typhimurium CysB, a LysR… · the same entry in another collection · chain B against B, TM-score 1.00
P06614 · AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator cysb (P06614) · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06614
Elsewhere: RCSB PDB 4LP2 · PDBe 4LP2 · UniProt P06614

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.