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Structural insight into RNA recognition by RRM1+2 domain of human etr- 3 protein

Analyse Structural insight into RNA recognition by RRM1+2 domain of human etr- 3 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4LMZ
Type
protein + RNA
Length
181 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (5'-R(*GP*CP*UP*GP*CP*GP*UP*AP*UP*UP*GP*UP*UP*UP*G)- 3'); Cugbp elav-like family…
UniProt
O95319

Structure

x-ray diffraction · 2 distinct chains · 28% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
BRNA (5'-R(*GP*CP*UP*GP*CP*GP*UP*AP*UP*UP*GP*UP*UP*UP*G)- 3')rna5——
ACugbp elav-like family member 2protein17628% helix, 30% strandO95319

Interfaces

1 interface between chains.

  • B–A · 535 Ų buried · 9 hydrogen bonds · protein-nucleic

Compared structures

  • 4LMZ · Structural insight into RNA recognition by RRM1+2 domain of human ETR-3 protein · the same entry in another collection · chain B against B, TM-score 1.00
  • O95319 · AlphaFold monomer V2.0 prediction for cugbp elav-like family member 2 (O95319) · a predicted model of the same protein · chain A against A, TM-score 0.78

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