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Crystal structure of an at-rich interactive domain-containing protein 3A (ARID3A) from homo sapiens at 2.21 a resolution
Analyse Crystal structure of an at-rich interactive domain-containing protein 3A… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4LJX
- Type
- protein
- Length
- 244 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- At-rich interactive domain-containing protein 3A
- UniProt
- Q99856
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 63% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | At-rich interactive domain-containing protein 3A | protein | 122 | 63% helix, 3% strand | Q99856 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 445 | 0.69 | 0.80 | 38 | empty |
| 2 | 211 | 0.49 | 0.75 | 28 | empty |
Interfaces
1 interface between chains.
- A–B · 619 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 4LJX · Crystal structure of an AT-rich interactive domain-containing protein 3A (ARID3A) from… · the same entry in another collection · chain A against A, TM-score 1.00
- Q99856 · AlphaFold monomer V2.0 prediction for at-rich interactive domain- containing protein 3A… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99856
- Elsewhere: RCSB PDB 4LJX · PDBe 4LJX · UniProt Q99856
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