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Crystal structure of inositol polyphosphate 5-phosphatase domain (IPP5C) of spsynaptojanin

Analyse Crystal structure of inositol polyphosphate 5-phosphatase domain (IPP5C) of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1I9Y
Type
protein
Length
336 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Phosphatidylinositol phosphate phosphatase
UniProt
O43001
Pockets
2 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 32% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APhosphatidylinositol phosphate phosphataseprotein33630% helix, 32% strandO43001

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1630.390.8015empty
2820.330.7518empty

Compared structures

  • 1I9Y · Crystal structure of inositol polyphosphate 5-phosphatase domain (IPP5C) of spsynaptojanin · the same entry in another collection · chain A against A, TM-score 1.00
  • O43001 · AlphaFold monomer V2.0 prediction for inositol-1,4,5-trisphosphate 5-phosphatase 1… · a predicted model of the same protein · chain A against A, TM-score 0.97

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