Research workbench
Crystal structure of human alpha-defensin 1 (HNP1) Y16A/F28A mutant
Analyse Crystal structure of human alpha-defensin 1 (HNP1) Y16A/F28A mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4LB1
- Type
- protein
- Length
- 120 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Neutrophil defensin 1
- UniProt
- P59665
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 57% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, E, A, B | Neutrophil defensin 1 | protein | 30 | 0% helix, 57% strand | P59665 |
Interfaces
6 interfaces between chains.
- D–E · 506 Ų buried · 10 hydrogen bonds · protein-protein
- A–B · 503 Ų buried · 9 hydrogen bonds · protein-protein
- D–A · 186 Ų buried · 0 hydrogen bonds · protein-protein
- E–B · 186 Ų buried · 0 hydrogen bonds · protein-protein
- E–A · 30 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 disulfide (disulfide).
Compared structures
- 4LB1 · Crystal structure of human alpha-defensin 1 (HNP1) Y16A/F28A mutant · the same entry in another collection · chain B against B, TM-score 1.00
- P59665 · AlphaFold monomer V2.0 prediction for neutrophil defensin 1 (P59665) · a predicted model of the same protein · chain D against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P59665
- Elsewhere: RCSB PDB 4LB1 · PDBe 4LB1 · UniProt P59665
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