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Crystal structure of FGF2-interacting protein from homo sapiens. northeast structural genomics consortium target HR9027A.

Analyse Crystal structure of FGF2-interacting protein from homo sapiens. northeast… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4L0R
Type: protein
Length: 147 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Centrosomal protein of 57 kda
UniProt: Q86XR8
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 2 distinct chains · 89% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Centrosomal protein of 57 kda	protein	74	91% helix, 0% strand	Q86XR8
B	Centrosomal protein of 57 kda	protein	73	88% helix, 0% strand	Q86XR8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	180	0.50	0.77	23	empty

Interfaces

1 interface between chains.

A–B · 540 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

4L0R · Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural… · the same entry in another collection · chain A against A, TM-score 1.00
Q86XR8 · AlphaFold monomer V2.0 prediction for centrosomal protein of 57 kda (Q86XR8) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86XR8
Elsewhere: RCSB PDB 4L0R · PDBe 4L0R · UniProt Q86XR8

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