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Structure of native yfke

Analyse Structure of native yfke in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4KJS
Type: protein
Length: 640 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cation exchanger yfke
UniProt: O34840
Pockets: 5 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 81% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cation exchanger yfke	protein	320	81% helix, 0% strand	O34840
B	Cation exchanger yfke	protein	320	82% helix, 0% strand	O34840

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1037	0.76	0.78	74	empty
2	326	0.61	0.78	44	empty
3	241	0.57	0.79	31	empty
4	71	0.34	0.75	15	empty
5	63	0.34	0.77	15	empty

Interfaces

1 interface between chains.

A–B · 528 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

4KJS · Structure of native YfkE · the same entry in another collection · chain A against A, TM-score 1.00
O34840 · AlphaFold monomer V2.0 prediction for CA(2+)/H(+) antiporter chaa (O34840) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O34840
Elsewhere: RCSB PDB 4KJS · PDBe 4KJS · UniProt O34840

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