Research workbench

Structure of aminotransferase ILVE2 from sinorhizobium meliloti complexed with plp

Analyse Structure of aminotransferase ILVE2 from sinorhizobium meliloti complexed with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4JXU
Type: protein
Length: 565 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative aminotransferase
EC: 2.6.1.42
UniProt: Q92RC2
Pockets: 9 · best druggability 0.57

Structure

x-ray diffraction · 2 distinct chains · 29% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative aminotransferase (EC 2.6.1.42)	protein	283	29% helix, 31% strand	Q92RC2
B	Putative aminotransferase (EC 2.6.1.42)	protein	282	29% helix, 30% strand	Q92RC2

Pockets

9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.57	0.88	28	empty
2	117	0.46	0.78	15	empty
3	102	0.45	0.79	14	empty
4	158	0.43	0.74	22	empty
5	147	0.43	0.74	24	empty

Interfaces

1 interface between chains.

A–B · 644 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 20 modified (engineered, cofactor).

Compared structures

4JXU · Structure of aminotransferase ilvE2 from Sinorhizobium meliloti complexed with PLP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92RC2
Elsewhere: RCSB PDB 4JXU · PDBe 4JXU · UniProt Q92RC2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.