Research workbench

Crystal structure analysis of arfaptin

Analyse Crystal structure analysis of arfaptin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1I49
Type: protein
Length: 402 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Arfaptin 2
UniProt: P53365
Pockets: 3 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 90% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Arfaptin 2	protein	201	90% helix, 0% strand	P53365

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	122	0.79	0.96	28	empty
2	94	0.52	0.83	19	empty
3	108	0.52	0.82	18	empty

Interfaces

1 interface between chains.

A–B · 2190 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

1I49 · Crystal structure analysis of arfaptin · the same entry in another collection · chain A against A, TM-score 1.00
P53365 · AlphaFold monomer V2.0 prediction for arfaptin-2 (P53365) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53365
Elsewhere: RCSB PDB 1I49 · PDBe 1I49 · UniProt P53365

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.