Research workbench
Alix V domain
Analyse Alix V domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4JJY
- Type
- protein
- Length
- 684 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Programmed cell death 6-interacting protein
- UniProt
- Q8WUM4
- Pockets
- 12 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Programmed cell death 6-interacting protein | protein | 342 | 75% helix, 0% strand | Q8WUM4 |
Pockets
12 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 296 | 0.69 | 0.83 | 36 | empty |
| 2 | 532 | 0.66 | 0.77 | 37 | empty |
| 3 | 237 | 0.66 | 0.83 | 33 | empty |
| 4 | 499 | 0.66 | 0.77 | 35 | empty |
| 5 | 255 | 0.58 | 0.78 | 40 | empty |
Interfaces
1 interface between chains.
- A–B · 305 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WUM4
- Elsewhere: RCSB PDB 4JJY · PDBe 4JJY · UniProt Q8WUM4
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