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Co-crystal structure of ICAP1 ptb domain in complex with a KRIT1 peptide

Analyse Co-crystal structure of ICAP1 ptb domain in complex with a KRIT1 peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4JIF
Type: protein
Length: 149 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Integrin beta-1-binding protein 1; Krev interaction trapped protein 1
UniProt: O14713, O00522

Structure

x-ray diffraction · 2 distinct chains · 26% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Integrin beta-1-binding protein 1	protein	130	25% helix, 44% strand	O14713
B	Krev interaction trapped protein 1	protein	19	37% helix, 32% strand	O00522

Interfaces

1 interface between chains.

A–B · 978 Å² buried · 21 hydrogen bonds · protein-protein

Compared structures

4JIF · Co-crystal structure of ICAP1 PTB domain in complex with a KRIT1 peptide · the same entry in another collection · chain A against A, TM-score 1.00
O14713 · AlphaFold monomer V2.0 prediction for integrin beta-1-binding protein 1 (O14713) · a predicted model of the same protein · chain A against A, TM-score 0.99
O00522 · AlphaFold monomer V2.0 prediction for krev interaction trapped protein 1 (O00522) · a predicted model of the same protein · chain B against A, TM-score 0.25

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14713
Every structure of UniProt O00522
Elsewhere: RCSB PDB 4JIF · PDBe 4JIF · UniProt O14713 · UniProt O00522

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