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Crystal structure of the mpmv tm retroviral fusion core

Analyse Crystal structure of the mpmv tm retroviral fusion core in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4JF3
Type: protein
Length: 182 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Envelope glycoprotein
UniProt: P07575
Ligands: CL
Pockets: 1 · best druggability 0.28

Structure

x-ray diffraction · 2 distinct chains · 84% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Envelope glycoprotein	protein	90	83% helix, 0% strand	P07575
B	Envelope glycoprotein	protein	92	84% helix, 0% strand	P07575

Ligands and binding sites

CL · Chloride ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.28	0.73	16	empty

Interfaces

1 interface between chains.

A–B · 367 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

4JF3 · Crystal structure of the mpmv tm retroviral fusion core · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07575
Elsewhere: RCSB PDB 4JF3 · PDBe 4JF3 · UniProt P07575

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