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Crystal structure of tyrosinase from bacillus megaterium N205A mutant
Analyse Crystal structure of tyrosinase from bacillus megaterium N205A mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4J6U
- Type
- protein
- Length
- 571 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosinase
- EC
- 1.14.18.1
- UniProt
- B2ZB02
- Pockets
- 4 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosinase (EC 1.14.18.1) | protein | 286 | 40% helix, 5% strand | B2ZB02 |
| B | Tyrosinase (EC 1.14.18.1) | protein | 285 | 39% helix, 6% strand | B2ZB02 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.71 | 0.94 | 18 | empty |
| 2 | 230 | 0.64 | 0.82 | 45 | empty |
| 3 | 105 | 0.41 | 0.77 | 24 | empty |
| 4 | 60 | 0.31 | 0.76 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1146 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 4J6U · Crystal Structure of Tyrosinase from Bacillus megaterium N205A mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2ZB02
- Elsewhere: RCSB PDB 4J6U · PDBe 4J6U · UniProt B2ZB02
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