Research workbench
Triple mutant sftavn
Analyse Triple mutant sftavn in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4J4S
- Type
- protein
- Length
- 962 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleocapsid protein
- UniProt
- I6WJ72
- Ligands
- NA
- Pockets
- 8 · best druggability 0.80
Structure
x-ray diffraction · 4 distinct chains · 64% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleocapsid protein | protein | 246 | 68% helix, 1% strand | I6WJ72 |
| B | Nucleocapsid protein | protein | 238 | 62% helix, 2% strand | I6WJ72 |
| C | Nucleocapsid protein | protein | 233 | 58% helix, 2% strand | I6WJ72 |
| D | Nucleocapsid protein | protein | 245 | 67% helix, 2% strand | I6WJ72 |
Ligands and binding sites
- NA · Sodium ion · metal · 8 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1142 | 0.80 | 0.81 | 106 | empty |
| 2 | 912 | 0.79 | 0.82 | 104 | NA |
| 3 | 389 | 0.72 | 0.83 | 35 | empty |
| 4 | 440 | 0.68 | 0.80 | 52 | empty |
| 5 | 149 | 0.46 | 0.77 | 32 | empty |
Interfaces
6 interfaces between chains.
- A–B · 2236 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 1922 Ų buried · 19 hydrogen bonds · protein-protein
- B–C · 295 Ų buried · 3 hydrogen bonds · protein-protein
- B–D · 212 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 145 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 4J4S · Triple mutant SFTAVN · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I6WJ72
- Elsewhere: RCSB PDB 4J4S · PDBe 4J4S · UniProt I6WJ72
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