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Solution structure of the N-terminal domain of riboflavin synthase from E. COLI

Analyse Solution structure of the N-terminal domain of riboflavin synthase from E. COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1I18
Type: protein
Length: 194 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Riboflavin synthase alpha chain
EC: 2.5.1.9
UniProt: P29015
Ligands: RBF
Pockets: 2 · best druggability 0.52

Structure

solution nmr · 1 distinct chain · 9% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Riboflavin synthase alpha chain (EC 2.5.1.9)	protein	97	9% helix, 45% strand	P29015

Ligands and binding sites

RBF · Riboflavin · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	224	0.52	0.77	34	empty
2	51	0.28	0.75	20	empty

Interfaces

1 interface between chains.

A–B · 956 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

1I18 · Solution structure of the N-terminal domain of riboflavin synthase from E. COLI · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29015
Elsewhere: RCSB PDB 1I18 · PDBe 1I18 · UniProt P29015

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