Research workbench
Crystal structure of H191L mutant of udp-glucose pyrophosphorylase from leishmania major
Analyse Crystal structure of H191L mutant of udp-glucose pyrophosphorylase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4J18
- Type
- protein
- Length
- 485 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-glucose pyrophosphorylase
- EC
- 2.7.7.9
- UniProt
- Q4QDU3
- Pockets
- 4 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-glucose pyrophosphorylase (EC 2.7.7.9) | protein | 485 | 33% helix, 27% strand | Q4QDU3 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 329 | 0.60 | 0.77 | 44 | empty |
| 2 | 324 | 0.54 | 0.75 | 38 | empty |
| 3 | 100 | 0.42 | 0.78 | 27 | empty |
| 4 | 55 | 0.26 | 0.72 | 13 | empty |
Compared structures
- 4J18 · Crystal structure of H191L mutant of UDP-glucose pyrophosphorylase from Leishmania major · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4QDU3
- Elsewhere: RCSB PDB 4J18 · PDBe 4J18 · UniProt Q4QDU3
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