Research workbench
Crystal structure of recombinant foot-and-mouth-disease virus A22- H2093C empty capsid
Analyse Crystal structure of recombinant foot-and-mouth-disease virus A22- H2093C empty… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4IV3
- Type
- protein
- Length
- 612 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein VP1; Capsid protein VP2; Capsid protein VP3; Capsid protein VP4
- UniProt
- Q6PN23
- Pockets
- 6 · best druggability 0.74
Structure
x-ray diffraction · 4 distinct chains · 11% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Capsid protein VP1 | protein | 178 | 15% helix, 31% strand | Q6PN23 |
| B | Capsid protein VP2 | protein | 207 | 10% helix, 43% strand | Q6PN23 |
| C | Capsid protein VP3 | protein | 221 | 9% helix, 31% strand | Q6PN23 |
| D | Capsid protein VP4 | protein | 6 | 0% helix, 0% strand | Q6PN23 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 586 | 0.74 | 0.81 | 67 | empty |
| 2 | 134 | 0.44 | 0.76 | 19 | empty |
| 3 | 120 | 0.43 | 0.76 | 16 | empty |
| 4 | 97 | 0.39 | 0.76 | 25 | empty |
| 5 | 79 | 0.34 | 0.75 | 21 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1110 Ų buried · 19 hydrogen bonds · protein-protein
- A–C · 1037 Ų buried · 18 hydrogen bonds · protein-protein
- B–C · 831 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 4IV3 · Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsid · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6PN23
- Elsewhere: RCSB PDB 4IV3 · PDBe 4IV3 · UniProt Q6PN23
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.