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Preliminary structural investigations of a malarial protein secretion system
Analyse Preliminary structural investigations of a malarial protein secretion system in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4IRF
- Type
- protein
- Length
- 289 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Malarial CLPB2 ATPASE/HSP101 protein
- UniProt
- Q8IIJ8
- Pockets
- 3 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 66% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Malarial CLPB2 ATPASE/HSP101 protein | protein | 145 | 66% helix, 4% strand | Q8IIJ8 |
| B | Malarial CLPB2 ATPASE/HSP101 protein | protein | 144 | 66% helix, 4% strand | Q8IIJ8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 373 | 0.73 | 0.84 | 39 | empty |
| 2 | 115 | 0.41 | 0.76 | 22 | empty |
| 3 | 81 | 0.35 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 505 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 4IRF · Preliminary structural investigations of a malarial protein secretion system · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IIJ8
- Elsewhere: RCSB PDB 4IRF · PDBe 4IRF · UniProt Q8IIJ8
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