Research workbench
Crystal structure of pseudomonas aeruginosa (strain: PAO1) type IV minor pilin fimu in space group P21
Analyse Crystal structure of pseudomonas aeruginosa (strain: PAO1) type IV minor pilin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4IPU
- Type
- protein
- Length
- 536 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fimu protein
- UniProt
- Q59652
- Pockets
- 5 · best druggability 0.68
Structure
x-ray diffraction · 4 distinct chains · 20% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fimu protein | protein | 137 | 21% helix, 34% strand | Q59652 |
| B | Fimu protein | protein | 134 | 20% helix, 34% strand | Q59652 |
| C | Fimu protein | protein | 136 | 21% helix, 34% strand | Q59652 |
| D | Fimu protein | protein | 129 | 18% helix, 34% strand | Q59652 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 441 | 0.68 | 0.80 | 57 | empty |
| 2 | 428 | 0.65 | 0.79 | 55 | empty |
| 3 | 273 | 0.52 | 0.75 | 46 | empty |
| 4 | 72 | 0.34 | 0.76 | 15 | empty |
| 5 | 68 | 0.33 | 0.76 | 13 | empty |
Interfaces
3 interfaces between chains.
- B–C · 598 Ų buried · 5 hydrogen bonds · protein-protein
- A–D · 431 Ų buried · 6 hydrogen bonds · protein-protein
- C–D · 167 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 4 disulfide, 4 modified (disulfide, engineered).
Compared structures
- 4IPU · Crystal structure of Pseudomonas aeruginosa (strain: PAO1) type IV minor pilin FimU in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q59652
- Elsewhere: RCSB PDB 4IPU · PDBe 4IPU · UniProt Q59652
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