Research workbench

Structure of the SPT16 middle domain reveals functional features of the histone chaperone fact

Analyse Structure of the SPT16 middle domain reveals functional features of the histone… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4IOY
Type: protein
Length: 243 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fact complex subunit SPT16
UniProt: P32558
Ligands: PO4
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Fact complex subunit SPT16	protein	243	26% helix, 40% strand	P32558

Ligands and binding sites

PO4 · Phosphate ion · ion · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	107	0.34	0.72	21	empty

Compared structures

4IOY · Structure of the Spt16 Middle Domain Reveals Functional Features of the Histone Chaperone… · the same entry in another collection · chain X against X, TM-score 1.00
P32558 · AlphaFold monomer V2.0 prediction for fact complex subunit SPT16 (P32558) · a predicted model of the same protein · chain X against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32558
Elsewhere: RCSB PDB 4IOY · PDBe 4IOY · UniProt P32558

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.