Research workbench
Crystal structure of S. mikatae STE24P
Analyse Crystal structure of S. mikatae STE24P in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4IL3
- Type
- protein
- Length
- 853 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- STE24P
- EC
- 3.4.24.84
- Ligands
- ZN
- Pockets
- 17 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 65% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | STE24P (EC 3.4.24.84) | protein | 422 | 65% helix, 5% strand | — |
| B | STE24P (EC 3.4.24.84) | protein | 431 | 65% helix, 5% strand | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
17 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 548 | 0.72 | 0.80 | 53 | empty |
| 2 | 324 | 0.71 | 0.84 | 45 | empty |
| 3 | 92 | 0.69 | 0.92 | 21 | empty |
| 4 | 584 | 0.65 | 0.75 | 61 | empty |
| 5 | 392 | 0.64 | 0.78 | 42 | empty |
Interfaces
1 interface between chains.
- A–B · 393 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 4IL3 · Crystal Structure of S. mikatae Ste24p · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4IL3 · PDBe 4IL3
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