Research workbench
Crystal structure of nucleocapsid protein encoded by the prototypic member of orthobunyavirus
Analyse Crystal structure of nucleocapsid protein encoded by the prototypic member of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4IJS
- Type
- protein + RNA
- Length
- 965 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoprotein; RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
- UniProt
- P16495
- Pockets
- 11 · best druggability 0.83
Structure
x-ray diffraction · 3 distinct chains · 50% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Nucleoprotein | protein | 232 | 50% helix, 6% strand | P16495 |
| E | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3') | rna | 10 | — | — |
| F, G, H | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3') | rna | 9 | — | — |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 257 | 0.83 | 0.95 | 39 | empty |
| 2 | 280 | 0.82 | 0.93 | 33 | empty |
| 3 | 226 | 0.81 | 0.94 | 34 | empty |
| 4 | 176 | 0.81 | 0.96 | 36 | empty |
| 5 | 237 | 0.49 | 0.75 | 30 | empty |
Interfaces
7 interfaces between chains.
- D–H · 1473 Ų buried · 19 hydrogen bonds · protein-nucleic
- C–G · 1431 Ų buried · 19 hydrogen bonds · protein-nucleic
- B–F · 1417 Ų buried · 13 hydrogen bonds · protein-nucleic
- A–E · 1377 Ų buried · 16 hydrogen bonds · protein-nucleic
- A–B · 319 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4IJS · Crystal structure of nucleocapsid protein encoded by the prototypic member of… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16495
- Elsewhere: RCSB PDB 4IJS · PDBe 4IJS · UniProt P16495
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.