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Crystal structures of the B1 domain of protein L from peptostreptococcus magnus with a tyrosine to tryptophan substitution

Analyse Crystal structures of the B1 domain of protein L from peptostreptococcus magnus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1HZ6
Type: protein
Length: 193 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein L
UniProt: Q51912
Pockets: 2 · best druggability 0.45

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein L	protein	67	31% helix, 42% strand	Q51912
B, C	Protein L	protein	63	33% helix, 44% strand	Q51912

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.45	0.84	19	empty
2	68	0.35	0.77	19	empty

Interfaces

3 interfaces between chains.

B–C · 594 Å² buried · 10 hydrogen bonds · protein-protein
A–B · 444 Å² buried · 5 hydrogen bonds · protein-protein
A–C · 59 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

1HZ6 · Crystal structures of the B1 domain of protein L from peptostreptococcus magnus with a… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q51912
Elsewhere: RCSB PDB 1HZ6 · PDBe 1HZ6 · UniProt Q51912

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