Research workbench

Histone H3 lysine 4 demethylating rice JMJ703 apo enzyme

Analyse Histone H3 lysine 4 demethylating rice JMJ703 apo enzyme in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4IGP
Type: protein
Length: 270 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: OS05G0196500 protein
UniProt: Q53WJ1
Ligands: FE
Pockets: 3 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	OS05G0196500 protein	protein	270	29% helix, 26% strand	Q53WJ1

Ligands and binding sites

FE · Fe (III) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	290	0.69	0.83	36	FE
2	91	0.40	0.77	16	empty
3	60	0.30	0.75	15	empty

Compared structures

4IGP · Histone H3 Lysine 4 Demethylating Rice JMJ703 apo enzyme · the same entry in another collection · chain A against A, TM-score 1.00
Q53WJ1 · AlphaFold monomer V2.0 prediction for lysine-specific demethylase JMJ703 (Q53WJ1) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q53WJ1
Elsewhere: RCSB PDB 4IGP · PDBe 4IGP · UniProt Q53WJ1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.