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Structure of ricin a chain bound with N-(N-(pterin-7-yl) carbonylglycyl)-L-phenylalanyl)-L-phenylalanine

Analyse Structure of ricin a chain bound with N-(N-(pterin-7-yl)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4HUP
Type: protein
Length: 263 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ricin
EC: 3.2.2.22
UniProt: P02879
Ligands: 19M, SO4
Pockets: 1 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Ricin (EC 3.2.2.22)	protein	263	41% helix, 22% strand	P02879

Ligands and binding sites

19M · (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-3-phenyl-propanoic acid · ligand · chains X
SO4 · Sulfate ion · ion · 2 copies · chains X
MLA · Malonic acid · additive · 2 copies · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	274	0.60	0.79	40	19M

Compared structures

4HUP · Structure of ricin A chain bound with N-(N-(pterin-7-yl)carbonylglycyl)-L-phenylalanyl)-L… · the same entry in another collection · chain X against X, TM-score 1.00

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Every structure of UniProt P02879
Elsewhere: RCSB PDB 4HUP · PDBe 4HUP · UniProt P02879

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