Research workbench

Re-refinement of the vault ribonucleoprotein particle

Analyse Re-refinement of the vault ribonucleoprotein particle in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4HL8
Type: protein
Length: 782 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major vault protein
UniProt: Q62667
Pockets: 6 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Major vault protein	protein	782	26% helix, 31% strand	Q62667

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	85	0.42	0.79	21	empty
2	96	0.36	0.74	15	empty
3	62	0.33	0.77	17	empty
4	53	0.31	0.76	14	empty
5	57	0.30	0.75	15	empty

Compared structures

4HL8 · Re-refinement of the vault ribonucleoprotein particle · the same entry in another collection · chain A against A, TM-score 1.00
Q62667 · AlphaFold monomer V2.0 prediction for major vault protein (Q62667) · a predicted model of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q62667
Elsewhere: RCSB PDB 4HL8 · PDBe 4HL8 · UniProt Q62667

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