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Crystal structure of arsab in the substrate-free state.

Analyse Crystal structure of arsab in the substrate-free state. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4HDN
Type: protein
Length: 661 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Arsa; Arsb
EC: 2.4.2.21
UniProt: F6MZ55, F6MZ56
Pockets: 6 · best druggability 0.69

Structure

x-ray diffraction · 2 distinct chains · 52% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Arsa (EC 2.4.2.21)	protein	335	52% helix, 11% strand	F6MZ55
B	Arsb (EC 2.4.2.21)	protein	326	52% helix, 11% strand	F6MZ56

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	341	0.69	0.82	57	empty
2	457	0.67	0.79	55	empty
3	171	0.56	0.80	21	empty
4	79	0.45	0.81	17	empty
5	103	0.42	0.76	14	empty

Interfaces

1 interface between chains.

A–B · 1759 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

4HDN · Crystal Structure of ArsAB in the Substrate-Free State. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F6MZ55
Every structure of UniProt F6MZ56
Elsewhere: RCSB PDB 4HDN · PDBe 4HDN · UniProt F6MZ55 · UniProt F6MZ56

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