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Crystal structure of casb from thermus thermophilus

Analyse Crystal structure of casb from thermus thermophilus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4H7A
Type: protein
Length: 310 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CRISPR-associated protein CSE2
UniProt: Q53VY0
Pockets: 2 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 66% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CRISPR-associated protein CSE2	protein	156	66% helix, 1% strand	Q53VY0
B	CRISPR-associated protein CSE2	protein	154	66% helix, 1% strand	Q53VY0

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.53	0.85	17	empty
2	98	0.48	0.80	18	empty

Interfaces

1 interface between chains.

A–B · 441 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

4H7A · Crystal structure of CasB from Thermus thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Q53VY0 · AlphaFold monomer V2.0 prediction for CRISPR-associated protein CSE2 (Q53VY0) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q53VY0
Elsewhere: RCSB PDB 4H7A · PDBe 4H7A · UniProt Q53VY0

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