Research workbench
Refined structures at 2 ångströms and 2.2 ångströms of the two forms of the H-protein, a lipoamide-containing protein of the glycine decarboxylase complex
Analyse Refined structures at 2 ångströms and 2.2 ångströms of the two forms of the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1HTP
- Type
- protein
- Length
- 131 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- H-protein
- EC
- 1.4.4.2
- UniProt
- P16048
- Ligands
- OSS
- Pockets
- 1 · best druggability 0.33
Structure
x-ray diffraction · 1 distinct chain · 25% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | H-protein (EC 1.4.4.2) | protein | 131 | 25% helix, 36% strand | P16048 |
Ligands and binding sites
- OSS · 6-(hydroxyethyldithio)-8-(aminomethylthio)octanoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.33 | 0.77 | 14 | OSS |
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 1HTP · Refined structures at 2 ångströms and 2.2 ångströms of the two forms of the H-protein, a… · the same entry in another collection · chain A against A, TM-score 1.00
- P16048 · AlphaFold monomer V2.0 prediction for glycine cleavage system H protein, mitochondrial… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16048
- Elsewhere: RCSB PDB 1HTP · PDBe 1HTP · UniProt P16048
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