Research workbench
Crystal structure of mimicry-recognizing 2D10 scfv with peptide
Analyse Crystal structure of mimicry-recognizing 2D10 scfv with peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4H0H
- Type
- protein
- Length
- 248 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 2D10 scfv; Peptide
- Pockets
- 3 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | 2D10 scfv | protein | 241 | 5% helix, 50% strand | — |
| D | Peptide | protein | 7 | 0% helix, 0% strand | — |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 109 | 0.41 | 0.76 | 25 | empty |
| 2 | 110 | 0.36 | 0.74 | 18 | empty |
| 3 | 80 | 0.32 | 0.74 | 21 | empty |
Interfaces
1 interface between chains.
- B–D · 581 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 4H0H · Crystal structure of mimicry-recognizing 2D10 scFv with peptide · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4H0H · PDBe 4H0H
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