Research workbench
Crystal structure of an rgs-rhogef from entamoeba histolytica
Analyse Crystal structure of an rgs-rhogef from entamoeba histolytica in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4GOU
- Type
- protein
- Length
- 507 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ehrgs-rhogef
- UniProt
- C4LYV4
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 60% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ehrgs-rhogef | protein | 507 | 60% helix, 10% strand | C4LYV4 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 647 | 0.74 | 0.80 | 43 | empty |
| 2 | 131 | 0.46 | 0.77 | 21 | empty |
| 3 | 69 | 0.37 | 0.78 | 17 | empty |
| 4 | 67 | 0.30 | 0.74 | 15 | empty |
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 4GOU · Crystal structure of an RGS-RhoGEF from Entamoeba histolytica · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C4LYV4
- Elsewhere: RCSB PDB 4GOU · PDBe 4GOU · UniProt C4LYV4
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