Research workbench
Crystal structure of oxa-45, a class D beta-lactamase with extended spectrum activity
Analyse Crystal structure of oxa-45, a class D beta-lactamase with extended spectrum… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4GN2
- Type
- protein
- Length
- 240 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oxacillinase
- EC
- 3.5.2.6
- UniProt
- Q7WZC7
- Pockets
- 2 · best druggability 0.42
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oxacillinase (EC 3.5.2.6) | protein | 240 | 39% helix, 25% strand | Q7WZC7 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 137 | 0.42 | 0.75 | 24 | empty |
| 2 | 57 | 0.23 | 0.71 | 24 | empty |
Modifications
Observed in the structure: 1 disulfide, 1 modified (disulfide, carboxylation).
Compared structures
- 4GN2 · Crystal Structure of OXA-45, a Class D beta-lactamase with extended spectrum activity · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7WZC7
- Elsewhere: RCSB PDB 4GN2 · PDBe 4GN2 · UniProt Q7WZC7
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