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Crystal structure of the complex of a human telomeric repeat G- quadruplex and N-methyl mesoporphyrin IX (P21212)

Analyse Crystal structure of the complex of a human telomeric repeat G- quadruplex and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4FXM
Type
DNA
Length
22 nucleotides
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'- D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)- 3')
Ligands
MMP, K

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'- D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)- 3')dna22——

Ligands and binding sites

  • MMP · N-methylmesoporphyrin · ligand · chains A
  • K · Potassium ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 4FXM · Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl… · the same entry in another collection · chain A against A, TM-score 1.00

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