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Crystal structure of an internalin (inlf) from listeria monocytogenes str. 4B F2365 at 1.91 a resolution
Analyse Crystal structure of an internalin (inlf) from listeria monocytogenes str. 4B… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4FMZ
- Type
- protein
- Length
- 681 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Internalin
- UniProt
- Q723P8
- Pockets
- 5 · best druggability 0.85
Structure
x-ray diffraction · 2 distinct chains · 22% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Internalin | protein | 340 | 21% helix, 13% strand | Q723P8 |
| B | Internalin | protein | 341 | 22% helix, 13% strand | Q723P8 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 13 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 789 | 0.85 | 0.88 | 118 | EDO |
| 2 | 115 | 0.58 | 0.84 | 22 | EDO |
| 3 | 77 | 0.55 | 0.87 | 21 | EDO |
| 4 | 123 | 0.49 | 0.79 | 18 | empty |
| 5 | 99 | 0.35 | 0.74 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 2062 Ų buried · 24 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 4FMZ · Crystal structure of an internalin (inlF) from Listeria monocytogenes str. 4b F2365 at… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q723P8
- Elsewhere: RCSB PDB 4FMZ · PDBe 4FMZ · UniProt Q723P8
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