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Crystal structure of plant protease DEG2
Analyse Crystal structure of plant protease DEG2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4FLN
- Type
- protein
- Length
- 1,418 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protease do-like 2, chloroplastic; Unknown peptide
- EC
- 3.4.21.-
- UniProt
- O82261
- Pockets
- 19 · best druggability 0.74
Structure
x-ray diffraction · 4 distinct chains · 17% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Protease do-like 2, chloroplastic (EC 3.4.21.-) | protein | 463 | 17% helix, 35% strand | O82261 |
| B | Protease do-like 2, chloroplastic (EC 3.4.21.-) | protein | 464 | 17% helix, 36% strand | O82261 |
| D, F | Unknown peptide | protein | 4 | 0% helix, 50% strand | — |
| E | Unknown peptide | protein | 20 | 0% helix, 25% strand | — |
Pockets
19 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 564 | 0.74 | 0.82 | 78 | empty |
| 2 | 528 | 0.71 | 0.80 | 55 | empty |
| 3 | 298 | 0.70 | 0.84 | 39 | empty |
| 4 | 511 | 0.70 | 0.80 | 63 | empty |
| 5 | 388 | 0.62 | 0.77 | 55 | empty |
Interfaces
6 interfaces between chains.
- B–E · 957 Ų buried · 13 hydrogen bonds · protein-protein
- B–C · 911 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 885 Ų buried · 15 hydrogen bonds · protein-protein
- A–C · 729 Ų buried · 15 hydrogen bonds · protein-protein
- A–D · 381 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O82261
- Elsewhere: RCSB PDB 4FLN · PDBe 4FLN · UniProt O82261
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