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Crystal structure of an artificial dimeric dnak complex

Analyse Crystal structure of an artificial dimeric dnak complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4F01
Type: protein
Length: 448 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chaperone protein dnak
UniProt: P0A6Y8
Pockets: 3 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chaperone protein dnak	protein	218	42% helix, 28% strand	P0A6Y8
B	Chaperone protein dnak	protein	230	36% helix, 27% strand	P0A6Y8

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	869	0.72	0.77	80	empty
2	128	0.51	0.80	20	empty
3	56	0.31	0.76	17	empty

Interfaces

1 interface between chains.

A–B · 1683 Å² buried · 30 hydrogen bonds · protein-protein

Compared structures

4F01 · Crystal structure of an artificial dimeric DnaK complex · the same entry in another collection · chain A against A, TM-score 1.00
P0A6Y8 · AlphaFold monomer V2.0 prediction for chaperone protein dnak (P0A6Y8) · a predicted model of the same protein · chain A against A, TM-score 0.47

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A6Y8
Elsewhere: RCSB PDB 4F01 · PDBe 4F01 · UniProt P0A6Y8

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