Research workbench

Solution structure of the DNA-binding domain of drosophila heat shock transcription factor

Analyse Solution structure of the DNA-binding domain of drosophila heat shock… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1HKT
Type: protein
Length: 106 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heat-shock transcription factor
UniProt: P22813
Pockets: 2 · best druggability 0.65

Structure

solution nmr · 1 distinct chain · 18% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heat-shock transcription factor	protein	106	18% helix, 11% strand	P22813

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	74	0.65	0.91	23	empty
2	62	0.37	0.78	15	empty

Compared structures

1HKT · Solution structure of the DNA-binding domain of drosophila heat shock transcription factor · the same entry in another collection · chain A against A, TM-score 1.00
P22813 · AlphaFold monomer V2.0 prediction for heat shock factor protein (P22813) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22813
Elsewhere: RCSB PDB 1HKT · PDBe 1HKT · UniProt P22813

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.