Research workbench
Crystal structure of a DUF1312 family protein (RUMGNA_02503) from ruminococcus gnavus atcc 29149 at 2.20 a resolution
Analyse Crystal structure of a DUF1312 family protein (RUMGNA_02503) from ruminococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4ESN
- Type
- protein
- Length
- 155 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein
- UniProt
- A7B4L9
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.55
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical protein | protein | 78 | 5% helix, 54% strand | A7B4L9 |
| B | Hypothetical protein | protein | 77 | 5% helix, 55% strand | A7B4L9 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A, B
- PE4 · 2-{2-[2-(2-{2-[2-(2-ethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.55 | 0.85 | 22 | empty |
| 2 | 97 | 0.45 | 0.79 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 653 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (engineered).
Compared structures
- 4ESN · Crystal structure of a DUF1312 family protein (RUMGNA_02503) from Ruminococcus gnavus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7B4L9
- Elsewhere: RCSB PDB 4ESN · PDBe 4ESN · UniProt A7B4L9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.